Understanding a drug’s mechanism of action (MoA) is critical for evaluating efficacy and safety. MoA analysis maps how compounds interact with molecular targets and modulate downstream signaling, capturing both on-target and off-target effects to support rational drug design and candidate prioritization.
With Hyperplex™, Assay Engineers simultaneously quantifies over 1,500 proteins and phospho-proteins, covering all major signaling pathways. This multiplexed profiling accelerates preclinical evaluation, reveals novel biomarkers, resistance pathways, regulatory mechanisms, and metabolic vulnerabilities, and provides a systems-level view of drug-induced cellular responses.
The resulting data create a reproducible, quantitative framework for distinguishing responders from non-responders, guiding biomarker selection, and informing combination therapy strategies. By integrating seamlessly into preclinical workflows, MoA analysis strengthens translational relevance and accelerates the development of targeted oncology therapies.
Main Benefit
Enable data-driven decisions through comprehensive mapping of drug mechanisms and cellular responses.
Schedule an individual life event with a scientist at Assay Engineers to identify your markers of interest.
